Room V contains artifacts from Sardara and its surrounding area: particularly interesting are the bronze archers from Sa Costa, unique in their distinctive clothing, ceramics from the Nuraghe Ortu Comidu, and Punic-Roman remains from the necropolises of Masoni Oneddu and Santa Caterina.

Room VI is entirely dedicated to the fortified complex of Monreale. It displays artifacts found during excavations of the keep, including valuable materials such as majolica and decorated ceramics imported from Spain, the Italian peninsula, and North Africa, as well as local productions in ceramics, wood, bone, and metal.

One display case particularly highlights aspects of daily life in the castle, showcasing bronze sewing pins and thimbles, buttons, dice, a flute, a cork tray, belt buckles, coins, nails, weapons, and locks.

The exhibition pit in the medieval room hosts a reconstruction of a hypothetical area for the production of building materials (roof tiles, bricks, and tiles) with various stages of processing, while late medieval originals are displayed in a dedicated case.

Graphic and photographic panels related to the castle and life in the Middle Ages complete the medieval section.